Evaluation of relationship between maximum SUV measured on 18F-FDG PET/CT with tumor pathological types, size, lymph node metastasis and distant metastasis in non-small cell lung cancer

Abstract Background Lung cancer is the most commonly diagnosed cancer, of which non-small cell lung (NSCLC) accounts for approximately 80% newly cancer. The prognosis tumors depends on early and accurate staging as well histopathological type tumor. It suggested that NSCLC with different types primary tumor sizes can elicit variable max.SUV values 18F-fluorodeoxyglucose-positron emission tomography/computed tomography (18F-FDG) PET/CT lymph nodes distant metastatic potential. In this study, we aim to evaluate relationship between maximum SUV measured pathological type, size, node metastasis, metastasis in NSCLC. Results This a cross-sectional analysis (FDG-PET/CT) findings 40 patients Statistical used determine correlation each nodal ( N ) M staging. were 25 (62.5%) adenocarcinomas, 12 (30%) squamous carcinomas 3 (7.5%) large carcinomas. size carcinoma group significantly higher than adenocarcinoma groups P = 0.000009). A significant positive was found tumoral size. Neither nor metastases involvement correlated max.SUV. Conclusions histologic subtype both strongly influence FDG uptake Nonetheless, cannot be regarded predictive or involvement.